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UPN Ref Technology
202 Biomimetic synthetic bone graft substitute
Synthetic bone graft substitutes, especially granules, lack of interaction with the human body and present high cristallinity compared to the human bone. The technology of interest here allows the manufacturing of a biomimetic calcium phosphate product, in granular form of different sizes, and phases proportion (Hydroxyapatite and B-TCP). Its superior specific surface area accelerates its degradation while its low cristallinity makes it much closer to the bone, makes it BIOMIMETIC.
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149 AN INNOVATIVE DISPOSABLE AIR-BUBBLE TRAP FOR IV-INFUSIONS FOR MEDICAL PROCEDURES
An innovative air-bubble, cheap, disposable trap used for IV medical infusions using nano-technology.
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143 Innovative encapsulation technologies for controlled release of functional ingredients and medicinals
A serie of core technologies that are based on patented encapsulation techniques designed for targeted and controlled release of vaccines, antibiotics, probiotics, nutrients and a wide range of sensitive food ingredients. Efficiency systems have proven to be efficient “DHL” ingredient delivery services in the human and animal body. In this way, this can help industry to enhance and develop new products with proven health claims.
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70 A safe, non-toxic, edible, organic nano-material for use in multiple applications
A safe, non-toxic, edible, organic, low-cost, nanomaterial that can be applied in many applications including: Personal Care, Cosmetics, Pharmaceutical, Nutraceutical, Agri-chemical and Food Products. The company's mission is to fulfill a rapidly growing global demand for eco-friendly polymers produced from sustainable sources that also enhance the performance of consumer products and provide new and unique properties.
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45 Aptamer-Based Therapeutics
The Innovator’s technology blocks the 3’ end of aptamers and other DNA oligonucleotides (e.g., antisense DNA) with proteins to stabilize these potentially therapeutic molecules in the body. The proteins can be simple serum albumins or more functional proteins such as the Fc tails of IgG antibodies or C1q to trigger the immune (complement) system to opsonize (phagocytize) or punch holes in cancer cells, Gram negative antibiotic-resistant bacteria and parasites. Specific aptamer sequences can also be used to coat deadly viruses such as West Nile and dengue viruses to curb their progression in vivo.
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43 Secretory E.coli protein production platform
A protein production platform has been established based on E.coli strains with the ability to efficiently export proteins of interest into the cell-free culture supernatant.
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42 Virus-like particle based vaccines
VLP based vaccines are developed via presentation of the antigen of choice on the surface of highly immunogenic virus-like particles produced in a safe, low-cost and vaccine applied yeast system. Proof-of-concept has been achieved for different target antigens in animal studies with excellent B- and T-cell specific immune response. The platform is broadly applicable for the development of human and veterinary vaccines.
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41 Yeast protein production platform
A protein production platform has been established based on Hansenula polymorpha (Pichia angusta) yeast strains with the ability to efficiently export proteins of interest into the cell-free culture supernatant.
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40 A bacteriophage lysates production technology
A method for the commercial production of bacteriophages composition. The method decreases the production volume and increases the production yields.
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38 Nanopore technology platform
A nanopore technology platform that enables high-throughput measurements of particles as they passes through a pore. The highly precise analytical nanotechnology uses tunable nanopore-based measurement to rapidly determine the size, charge and concentration of particle populations with individual particle resolution.
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